IL-6 inhibition in RA — mechanism, monitoring, and differentiating the agents
IL-6 inhibitors can quiet RA—and mask CRP/ESR signals. Learn 4 monitoring clues on infection, lipids, neutrophils, and CDAI for safer care at the next visit.
Diagnostics and Testing
Seronegative RA — diagnosis, prognosis, and treatment considerations
RF/anti-CCP negative? Learn how seronegative RA is diagnosed with 2010 criteria, imaging, and treat-to-target care—avoid mimics, missed synovitis, DMARD delays.
Hydroxychloroquine dosing and retinal toxicity — the updated guidance
Dose hydroxychloroquine safely with the 5 mg/kg actual-weight rule, retinal toxicity risk stats, OCT screening timing, and tips to protect lupus control well.
Subclinical synovitis on ultrasound — clinical relevance or overreach?
Ultrasound can spot subclinical synovitis in RA—but ARCTIC shows why Doppler findings alone shouldn’t trigger escalation. Learn when imaging helps most.
Positive ANA Test: What It Means and What Comes Next
Positive ANA Test: What It Means and What Comes Next A positive antinuclear antibody test can create more anxiety than
What complement levels actually tell us in lupus
Low C3/C4 in lupus can signal kidney flares—but not alone. Learn how trends, urinalysis, anti-dsDNA and 2023 EULAR guidance shape care—and when to seek care.